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KMID : 0882420120830020243
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Korean Journal of Medicine
2012 Volume.83 No. 2 p.243 ~ p.248
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A Case of Mycobacterium Massiliense Infection Presenting as Recurrent Pneumonia in Sjogren’s Syndrome
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Seo Ji-Yung
Lee Byung-Hee
Lee Jang-Won
Lee Myung-Hee
Oh Sook-Kyung
Cho Hyun-Myung
Lee Choong-Won
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Abstract
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Mycobacterium massiliense is an emerging pathogen that is increasingly reported as a causative agent occurring during medical procedures, at surgical sites, and intramuscularly [1]. Although previously classified as part of M. abscessus, M. massiliense has recently been identified as a new species of rapidly growing nontuberculous mycobacteria [1,3] via a comparative sequence analysis of rpoB and hsp65 [3,5]. However, the clinical manifestations of M. massiliense have not been well characterized. We report here in a case of recurrent pneumonia for 3 years that improved with antibiotic treatment for M. massiliense in a 37-year-old woman with Sjogren’s syndrome. The patient showed a substantial response to treatment with a combination of antimicrobial therapies comprising clarithromycin and amikacin without cefoxitin for 6 months. This is the first report of pulmonary infection of M. massiliense with Sjogren’s syndrome in Korea.
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KEYWORD
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Nontuberculous mycobacteria, Mycobacterium massiliense, Pneumonia, Sjogren’s syndrome
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